Intrinsic factor is secreted by which tissue to aid vitamin B12 absorption?

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Study for the HOSA Foundations of Nutrition Test. Enhance your knowledge with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Multiple Choice

Intrinsic factor is secreted by which tissue to aid vitamin B12 absorption?

Explanation:
Intrinsic factor is produced by parietal cells in the stomach’s gastric mucosa. This special protein binds vitamin B12 in the stomach, forming a complex that protects B12 as it travels to the terminal ileum, where it is absorbed through receptor-mediated uptake. Without intrinsic factor, B12 absorption is severely impaired, leading to pernicious anemia. The small intestine mucosa does not secrete intrinsic factor, and the liver and pancreas do not provide this function.

Intrinsic factor is produced by parietal cells in the stomach’s gastric mucosa. This special protein binds vitamin B12 in the stomach, forming a complex that protects B12 as it travels to the terminal ileum, where it is absorbed through receptor-mediated uptake. Without intrinsic factor, B12 absorption is severely impaired, leading to pernicious anemia. The small intestine mucosa does not secrete intrinsic factor, and the liver and pancreas do not provide this function.

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